Gene information
Official symbol GABRG2
Official full name gamma-aminobutyric acid type A receptor subunit gamma2
Gene type protein-coding gene
Chromosome5q34
Gene familyGamma-aminobutyric acid type A receptor subunits
Resources
Entrez Gene 2566
HGNC HGNC:4087
Ensembl ENSG00000113327
Vega OTTHUMG00000130350
UCSC uc003lyy.5
GO terms: 67 records
GO Description Category LogP Number of genes Detail
GO:0004890 GABA-A receptor activity GO Molecular Functions -2.56582611 3 More
GO:0005216 ion channel activity GO Molecular Functions -2.12987867 14 More
GO:0005230 extracellular ligand-gated ion channel activity GO Molecular Functions -1.61683205 4 More
GO:0005237 inhibitory extracellular ligand-gated ion channel activity GO Molecular Functions -2.87480819 3 More
GO:0005253 anion channel activity GO Molecular Functions -1.99792626 5 More
GO:0005254 chloride channel activity GO Molecular Functions -1.59770764 4 More
GO:0006821 chloride transport GO Biological Processes -1.70687084 5 More
GO:0007214 gamma-aminobutyric acid signaling pathway GO Biological Processes -2.12450567 3 More
GO:0007268 chemical synaptic transmission GO Biological Processes -4.44678751 35 More
GO:0007416 synapse assembly GO Biological Processes -2.37502879 6 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0008503 benzodiazepine receptor activity GO Molecular Functions -3.29594651 3 More
GO:0009791 post-embryonic development GO Biological Processes -4.81501809 14 More
GO:0015103 inorganic anion transmembrane transporter activity GO Molecular Functions -2.09965422 7 More
GO:0015108 chloride transmembrane transporter activity GO Molecular Functions -1.77380598 5 More
GO:0015267 channel activity GO Molecular Functions -2.12225487 15 More
GO:0015276 ligand-gated ion channel activity GO Molecular Functions -3.44721899 9 More
GO:0015318 inorganic molecular entity transmembrane transporter activity GO Molecular Functions -2.11605072 20 More
GO:0015698 inorganic anion transport GO Biological Processes -1.84892626 7 More
GO:0016917 GABA receptor activity GO Molecular Functions -2.37908792 3 More
GO:0022803 passive transmembrane transporter activity GO Molecular Functions -2.11455525 15 More
GO:0022824 transmitter-gated ion channel activity GO Molecular Functions -1.90014847 4 More
GO:0022834 ligand-gated channel activity GO Molecular Functions -3.44721899 9 More
GO:0022835 transmitter-gated channel activity GO Molecular Functions -1.90014847 4 More
GO:0022836 gated channel activity GO Molecular Functions -2.68852033 13 More
GO:0022851 GABA-gated chloride ion channel activity GO Molecular Functions -3.06676630 3 More
GO:0030424 axon GO Cellular Components -6.14132550 54 More
GO:0030425 dendrite GO Cellular Components -4.55233052 48 More
GO:0030534 adult behavior GO Biological Processes -6.59104580 21 More
GO:0031252 cell leading edge GO Cellular Components -1.97716247 28 More
GO:0032589 neuron projection membrane GO Cellular Components -1.92506134 4 More
GO:0032590 dendrite membrane GO Cellular Components -2.48632122 4 More
GO:0034329 cell junction assembly GO Biological Processes -3.18336526 12 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0034707 chloride channel complex GO Cellular Components -2.11523204 4 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0050808 synapse organization GO Biological Processes -6.17744712 32 More
GO:0051932 synaptic transmission, GABAergic GO Biological Processes -2.37908792 3 More
GO:0060078 regulation of postsynaptic membrane potential GO Biological Processes -2.74505261 11 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0097060 synaptic membrane GO Cellular Components -5.94418548 20 More
GO:0097447 dendritic tree GO Cellular Components -4.82959150 49 More
GO:0098656 anion transmembrane transport GO Biological Processes -1.61106579 8 More
GO:0098661 inorganic anion transmembrane transport GO Biological Processes -1.97776028 5 More
GO:0098916 anterograde trans-synaptic signaling GO Biological Processes -4.44678751 35 More
GO:0098936 intrinsic component of postsynaptic membrane GO Cellular Components -4.76116234 10 More
GO:0098948 intrinsic component of postsynaptic specialization membrane GO Cellular Components -4.56568042 8 More
GO:0098960 postsynaptic neurotransmitter receptor activity GO Molecular Functions -2.86473787 9 More
GO:0098978 glutamatergic synapse GO Cellular Components -4.83590061 31 More
GO:0098982 GABA-ergic synapse GO Cellular Components -3.15908473 6 More
GO:0099055 integral component of postsynaptic membrane GO Cellular Components -4.91964814 10 More
GO:0099060 integral component of postsynaptic specialization membrane GO Cellular Components -4.68780123 8 More
GO:0099095 ligand-gated anion channel activity GO Molecular Functions -2.63563271 3 More
GO:0099240 intrinsic component of synaptic membrane GO Cellular Components -5.23284212 12 More
GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential GO Molecular Functions -3.0845403 5 More
GO:0099536 synaptic signaling GO Biological Processes -6.00976162 42 More
GO:0099537 trans-synaptic signaling GO Biological Processes -5.17038357 38 More
GO:0099572 postsynaptic specialization GO Cellular Components -2.67743186 13 More
GO:0099634 postsynaptic specialization membrane GO Cellular Components -4.18233935 9 More
GO:0099699 integral component of synaptic membrane GO Cellular Components -4.78109966 11 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1902476 chloride transmembrane transport GO Biological Processes -2.50383130 5 More
GO:1902710 GABA receptor complex GO Cellular Components -2.43794115 3 More
GO:1902711 GABA-A receptor complex GO Cellular Components -2.56582611 3 More
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO Molecular Functions -2.30459914 4 More
GO:1990351 transporter complex GO Cellular Components -2.10211936 13 More
KEGG pathways: 4 records
KEGG Description Category LogP Number of genes Detail
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04727 GABAergic synapse KEGG Pathway -1.95788592 5 More
hsa05032 Morphine addiction KEGG Pathway -3.96184640 13 More
hsa05033 Nicotine addiction KEGG Pathway -2.52579963 4 More
Drug-Gene interaction
view
Related drugs: 66 records
Drug name Interaction type Source PMID View
acamprosate calcium ChemblInteractions view
adinazolam potentiator TEND 61484006320036 view
adipiplon partial agonist ChemblInteractions view
alprazolam positive modulator ChemblInteractionsTEND view
azietomidate DTC 16884293 view
brexanolone TTD view
bromazepam potentiator TEND 18384456 view
butabarbital sodium positive modulator ChemblInteractions view
butalbital positive modulator ChemblInteractions view
chembl1077391 DTC 19762240 view
chembl1518572 TTD view
chembl2170369 DTC 21751815 view
chlordiazepoxide positive modulator ChemblInteractionsTEND view
chlordiazepoxide hydrochloride positive modulator ChemblInteractions view
cinolazepam potentiator TEND 7849137 view
clobazam positive modulator ChemblInteractionsTEND view
clonazepam positive modulator ChemblInteractionsTEND view
clorazepate dipotassium positive modulator ChemblInteractions view
clorazepic acid TEND view
clotiazepam potentiator TEND 188556141059223518604239 view
desflurane positive modulator ChemblInteractions view
diazepam positive modulatorpotentiator ChemblInteractionsTEND 1838445611752090 view
enflurane ChemblInteractions view
estazolam potentiatorpositive modulator ChemblInteractionsTEND 6398542889803 view
eszopiclone positive modulator ChemblInteractions view
ethchlorvynol ChemblInteractions view
etomidate DTCChemblInteractions 1688429320704351 view
fludiazepam potentiator TEND 2857046 view
flumazenil antagonist ChemblInteractions 17974564869392211864636 view
flurazepam potentiator TEND 1838445611752090 view
glutethimide ChemblInteractions view
halazepam positive modulatorpotentiator ChemblInteractionsTEND 67383022867566 view
halothane positive modulator ChemblInteractions view
isoflurane positive modulator ChemblInteractions view
isonipecotic acid DTC 25038482 view
lorazepam positive modulator ChemblInteractionsTEND view
lorediplon positive modulator ChemblInteractions view
meprobamate agonist ChemblInteractions view
metharbital positive modulator ChemblInteractions view
methohexital sodium positive modulator ChemblInteractions view
methoxyflurane ChemblInteractions view
methyprylon positive modulator ChemblInteractions view
midazolam potentiator TEND 1838445611752090 view
midazolam hydrochloride positive modulator ChemblInteractions view
nitrazepam potentiator TEND 1838445611752090 view
oxazepam potentiatorpositive modulator ChemblInteractionsTEND 1838445611752090 view
pentobarbital positive modulator ChemblInteractions view
pentobarbital sodium positive modulator ChemblInteractions view
pf-06372865 agonist ChemblInteractions view
prazepam positive modulatorpotentiator ChemblInteractionsTEND 7773620 view
primidone positive modulator ChemblInteractions view
propofol positive modulator ChemblInteractions view
quazepam potentiatorpositive modulator ChemblInteractionsTEND 30176902892106 view
resequinil inverse agonist ChemblInteractions view
secobarbital sodium positive modulator ChemblInteractions view
sevoflurane positive modulator ChemblInteractions view
talbutal positive modulator ChemblInteractions view
temazepam positive modulatorpotentiator ChemblInteractionsTEND 1838445620138190 view
thiamylal sodium positive modulator ChemblInteractions view
thiocolchicoside TTD view
thiopental sodium positive modulator ChemblInteractions view
topiramate ChemblInteractions view
triazolam positive modulatorpotentiator ChemblInteractionsTEND 1838445611752090 view
triclofos sodium ChemblInteractions view
zaleplon positive modulator ChemblInteractions view
zolpidem tartrate positive modulator ChemblInteractions view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
Chr5:162078566 hypomethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
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